Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ABL2 | P42684 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108026 | 1.00 | SRC (0.44) | SRCABL1EGFRABL2KDR | |
| SCHEMBL30582584 | 0.89 | SRC (0.47) | SRCABL1EGFRABL2KDR | |
| SCHEMBL26106994 | 0.89 | KCNH2 (0.39) | SRCABL1EGFRABL2KDR | |
| SCHEMBL26106140 | 0.89 | KIT (0.35) | SRCABL1KDRTEKLCK | |
| SCHEMBL30582578 | 0.89 | KIT (0.35) | SRCABL1KDRTEKLCK | |
| SCHEMBL30582625 | 0.89 | KCNH2 (0.39) | SRCABL1EGFRABL2KDR | |
| SCHEMBL26109072 | 0.89 | SRC (0.47) | SRCABL1EGFRABL2KDR | |
| SCHEMBL26106044 | 0.89 | CCNT1 (0.38) | SRCABL1EGFRKDRRIPK2 | |
| SCHEMBL30582605 | 0.89 | CCNT1 (0.38) | SRCABL1EGFRKDRRIPK2 | |
| SCHEMBL26107050 | 0.89 | LCK (0.40) | SRCEGFRKDRTEKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |