Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591939 | 0.84 | APP (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL26107496 | 0.84 | APP (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL26106128 | 0.81 | HTR1A (0.67) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL26496614 | 0.76 | HTR1A (0.47) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26107260 | 0.76 | HTR2C (0.47) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL26105526 | 0.76 | PDE10A (0.33) | — | |
| SCHEMBL30591679 | 0.75 | TEAD1 (0.39) | — | |
| SCHEMBL26103340 | 0.75 | TEAD1 (0.39) | — | |
| SCHEMBL30591841 | 0.75 | PDE10A (0.38) | — | |
| Hydrochloric Acid SCHEMBL31615915 | 0.75 | HTR2C (0.54) | HTR1ASLC6A2SLC6A4SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250206722-A1 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE | 2025-06-26 | — | — | US | disclosed |
| CN-119403551-A | Small molecule inhibitors of TEA domain family members | 斯克里普斯研究学院 | 2025-02-07 | — | — | CN | disclosed |
| EP-4496570-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | The Scripps Research Institute (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206722-A1 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | YAP1, TEAD1, TEAD2 | HTR1A 4543/4885SLC6A2 3448/4885SLC6A4 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.