Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.52 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.52 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.43 |
| ▸ | MICA | Q29983 | 1/20 | 0.43 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028853 | 0.79 | SMN1; SMN2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL5966721 | 0.79 | SMN1; SMN2 (0.55) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL25694655 | 0.78 | KIF11 (0.43) | ABCC9ABCC8KCNJ11KCNJ8SIGMAR1 | |
| SCHEMBL29454964 | 0.78 | KDM4E (0.44) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL22322904 | 0.77 | SMN1; SMN2 (0.53) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL1070786 | 0.77 | SMN1; SMN2 (0.50) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL2009716 | 0.76 | CA12 (0.43) | HTTKIF11KDM4EALDH1A1LMNA | |
| SCHEMBL13225982 | 0.76 | SMN1; SMN2 (0.49) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL420682 | 0.76 | SMN1; SMN2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 | |
| SCHEMBL5046816 | 0.76 | SMN1; SMN2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946236-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20120094830-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-8101550-B2 | Anthranilic acid diamide derivative with hetero-aromatic and hetero-cyclic substituents | BAYER CROPSCIENCE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029478-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | DDT, ANTXR2, QDPR | ABCC9 882/4885ABCC8 1569/4885KCNJ11 2912/4885 |
| US-20120094830-A1 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS | DDT, ANTXR2, QDPR | ABCC9 882/4885ABCC8 1569/4885KCNJ11 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.