Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HAT1 | O14929 | 2/20 | 0.39 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26111945 | 1.00 | MEN1 (0.39) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL30621225 | 0.80 | KMT2A (0.58) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL22071670 | 0.80 | KMT2A (0.58) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL22071682 | 0.80 | KMT2A (0.58) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL26110110 | 0.77 | CASP1 (0.47) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL26110100 | 0.77 | CASP1 (0.47) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL16239990 | 0.70 | MEN1 (0.59) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL22071679 | 0.70 | MEN1 (0.59) | MEN1USP2KMT2AKDM4ECASP1 | |
| Water SCHEMBL16240843 | 0.69 | MEN1 (0.58) | MEN1USP2KMT2AKDM4ECASP1 | |
| SCHEMBL22071729 | 0.67 | MEN1 (0.53) | MEN1USP2KMT2AKDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191379-A1 | 3,4-DIHYDROQUINOXALINE-2-CARBOXIMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTING OR TREATING CANCER DISEASE | 재단법인 대구경북첨단의료산업진흥재단 | 2023-10-05 | — | — | WO | disclosed |