SCHEMBL26112100

SCHEMBL26112100

NCc1ccc(Cc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.58
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
ALDH1A1 P00352 1/20 0.54
PLA2G10 O15496 1/20 0.53
PLA2G2A P14555 1/20 0.53
HDAC3 O15379 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
NCOR2 Q9Y618 1/20 0.53
TSHR P16473 2/20 0.52
TP53 P04637 1/20 0.52
LOXL2 Q9Y4K0 4/20 0.52
KMT2A Q03164 2/20 0.50
LMNA P02545 1/20 0.48
F10 P00742 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminomethylbenzoic Acid SCHEMBL9344424 0.93 ALDH1A1 (0.60) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL38758 0.93 ALDH1A1 (0.60) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL28342619 0.91 ALDH1A1 (0.58) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL1206230 0.91 ALDH1A1 (0.58) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL7428232 0.91 ALDH1A1 (0.58) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL1567841 0.91 ALDH1A1 (0.58) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL11755138 0.89 ALDH1A1 (0.61) SRD5A2ALDH1A1HDAC3HDAC6NCOR2
SCHEMBL68390 0.89 SRD5A2 (0.69) SRD5A2CA12CA1CA2CA9
SCHEMBL1851387 0.87 HRH3 (0.61) SRD5A2CA12CA1CA2CA9
Aminomethylbenzoic Acid SCHEMBL29271526 0.87 ALDH1A1 (0.59) SRD5A2ALDH1A1HDAC3HDAC6NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196898-A1 BETA GLOBIN MIMETIC PEPTIDES AND THEIR USE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-12 WO disclosed