Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levacetylleucine SCHEMBL18283362 | 0.90 | ALDH1A1 (0.79) | ALDH1A1SLC7A5SLC1A3SLC1A2KDM4E | |
| Acetylleucine SCHEMBL20898469 | 0.90 | ALDH1A1 (0.79) | ALDH1A1SLC7A5SLC1A3SLC1A2KDM4E | |
| D-Leucine SCHEMBL3416402 | 0.83 | SLC7A5 (0.64) | ALDH1A1SLC7A5MMESLC1A3SLC1A2 | |
| SCHEMBL30600472 | 0.83 | MME (0.61) | ALDH1A1SLC7A5MMESLC1A3SLC1A2 | |
| SCHEMBL8945299 | 0.83 | MME (0.61) | ALDH1A1SLC7A5MMESLC1A3SLC1A2 | |
| SCHEMBL8945304 | 0.83 | MME (0.61) | ALDH1A1SLC7A5MMESLC1A3SLC1A2 | |
| SCHEMBL17327497 | 0.82 | ALDH1A1 (0.64) | ALDH1A1SLC7A5SLC1A3SLC1A2KDM4E | |
| SCHEMBL79542 | 0.82 | MAPT (0.64) | ALDH1A1MMETGFBR1KDM4EMAPT | |
| SCHEMBL2122264 | 0.82 | MAPT (0.64) | ALDH1A1MMETGFBR1KDM4EMAPT | |
| SCHEMBL79541 | 0.82 | MAPT (0.64) | ALDH1A1MMETGFBR1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185709-A1 | MARKER COMBINATION FOR DIAGNOSING ADVANCED COLORECTAL TUMOR, AND APPLICATION THEREOF | 武汉迈特维尔医学科技有限公司 | 2023-10-05 | — | — | WO | claimed |
| CN-116430047-A | Metabolic marker for evaluating colorectal cancer and colorectal cancer risk in progressive stage and application thereof | 武汉迈特维尔医学科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| WO-2023185709-A1 | MARKER COMBINATION FOR DIAGNOSING ADVANCED COLORECTAL TUMOR, AND APPLICATION THEREOF | 武汉迈特维尔医学科技有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-116430047-A | Metabolic marker for evaluating colorectal cancer and colorectal cancer risk in progressive stage and application thereof | 武汉迈特维尔医学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |