Liquiritin

Liquiritin

SCHEMBL26113334

O=C1C[C@@H](c2ccc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc2)Oc2cc(O)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 1/20 1.00
▸ P4HB P07237 1/20 1.00
▸ TRPV1 Q8NER1 1/20 1.00
▸ PTPN1 P18031 4/20 0.70
▸ SLCO2B1 O94956 2/20 0.70
▸ SYNJ2 O15056 1/20 0.63
▸ XDH P47989 1/20 0.60
▸ KDM1A O60341 1/20 0.59
▸ CYP19A1 P11511 6/20 0.58
▸ TUBB4A P04350 1/20 0.58
▸ TUBB P07437 1/20 0.58
▸ YES1 P07947 1/20 0.58
▸ TUBA3C P0DPH7 1/20 0.58
▸ TUBA1B P68363 1/20 0.58
▸ TUBA4A P68366 1/20 0.58
▸ TUBB4B P68371 1/20 0.58
▸ TUBB3 Q13509 1/20 0.58
▸ TUBB2A Q13885 1/20 0.58
▸ TUBB8 Q3ZCM7 1/20 0.58
▸ TUBA3E Q6PEY2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Liquiritin SCHEMBL13906116 1.00 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL13931703 1.00 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL29536850 1.00 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL24209243 1.00 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL15091079 1.00 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL24835038 1.00 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL29351306 0.94 TRPA1 (0.89) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL10926327 0.88 TRPA1 (0.79) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL27939664 0.88 TRPA1 (0.79) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL31504735 0.88 TRPA1 (0.79) TRPA1P4HBTRPV1PTPN1SLCO2B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746852-A1 LIPID AGGREGATES FOR INTRAARTICULAR ADMINISTRATION Universität Bern (CH) 2026-05-27 — — EP claimed
CN-122072266-A Detection method of traditional Chinese medicine composition for treating lung heat cough and asthma 贵州三力制药股份有限公司 2026-05-22 — — CN claimed
CN-121570483-A Application of liquiritin in preparing medicament for preventing/treating allergic asthma 新疆维吾尔自治区药物研究院 2026-02-27 — — CN claimed
EP-3845065-B1 BIPHENYL COMPOUND-CONTAINING LIQUID PREPARATION AND APPLICATION THEREOF SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) 2026-01-14 — — EP claimed
EP-3888670-B1 DRUG FOR TREATING LEUKOPENIA, PREPARATION METHOD THEREFOR AND USE THEREOF MONYAN PHARMACEUTICAL CO LTD (CN) 2025-12-24 — — EP claimed
US-12446580-B2 Liquid formulation of biphenyl-containing compound and application thereof SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) 2025-10-21 — — US claimed
US-12409192-B2 Traditional Chinese medicine composition and use thereof JIANGSU KANION PHARMACEUTICAL CO., LTD (CN) 2025-09-09 — — US claimed
CN-120138149-A Use of PTPRG as a marker for diagnosing colorectal cancer and as a therapeutic target 宿州学院 2025-06-13 — — CN claimed
CN-120118997-A MiRNA marker for diagnosing and treating colorectal cancer and application of miRNA marker in preparation of medicines for preventing and treating colorectal cancer 宿州学院 2025-06-10 — — CN claimed
US-20250177467-A1 COMPOSITIONS AND METHODS FOR MODULATING NUCLEAR FACTOR OF ACTIVATED T-CELLS (NFAT) ACTIVITY OF T CELLS UNIV YALE (US) 2025-06-05 — — US claimed
CN-114097939-A Sustained-release tablet matrix and preparation method and application thereof 上海佩格医院管理有限公司 2022-03-01 — — CN claimed
CN-114088823-A Method for measuring content of multi-index components in Tongtian oral liquid 鉴甄检测技术(上海)有限公司 2022-02-25 — — CN claimed
CN-109856276-B Content determination method of Qipi pills 广西壮族自治区食品药品检验所 2022-02-25 — — CN claimed
CN-110873774-B Method for establishing high performance liquid chromatography fingerprint spectrum of cough-relieving immediate effect pills 山西华康药业股份有限公司 2022-02-18 — — CN claimed
CN-114034797-A Method for measuring content of flower components of dendrobium nobile lindl 遵义医科大学 2022-02-11 — — CN claimed
CN-114034798-A Red water dendrobium stem flower fingerprint construction and content determination method 遵义医科大学 2022-02-11 — — CN claimed
CN-111281944-B Xiebai powder composition and preparation method and quality detection method thereof 武汉同济现代医药科技股份有限公司 2022-02-08 — — CN claimed
CN-114002366-A Large gentiana root decoction standard water extract, preparation and quality control evaluation method thereof 京津冀联创药物研究(北京)有限公司 2022-02-01 — — CN claimed
CN-112641916-B Traditional Chinese medicine ointment formula for building body and preparation method thereof 辽宁上药好护士药业(集团)有限公司 2022-02-01 — — CN claimed
CN-113956797-A Jet polishing solution and polishing method for oxygen-free copper microstructure functional surface 清华大学 2022-01-21 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12446580-B2 Liquid formulation of biphenyl-containing compound and application thereof ABCG2, CHIA, DDT TRPA1 356/4885P4HB 3813/4885TRPV1 1132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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