SCHEMBL29351306

SCHEMBL29351306

O=C1C[C@@H](c2ccc(O)cc2)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc21

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 1/20 0.89
▸ P4HB P07237 1/20 0.89
▸ TRPV1 Q8NER1 1/20 0.89
▸ PTPN1 P18031 3/20 0.76
▸ SLCO2B1 O94956 3/20 0.76
▸ SYNJ2 O15056 1/20 0.66
▸ CYP19A1 P11511 5/20 0.61
▸ GSK3B P49841 1/20 0.61
▸ UBE2N P61088 1/20 0.61
▸ KDM1A O60341 1/20 0.61
▸ XDH P47989 1/20 0.60
▸ TYR P14679 2/20 0.57
▸ TUBB4A P04350 1/20 0.56
▸ TUBB P07437 1/20 0.56
▸ YES1 P07947 1/20 0.56
▸ TUBA3C P0DPH7 1/20 0.56
▸ TUBA1B P68363 1/20 0.56
▸ TUBA4A P68366 1/20 0.56
▸ TUBB4B P68371 1/20 0.56
▸ TUBB3 Q13509 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Liquiritin SCHEMBL26113334 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL13906116 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL29536850 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL24209243 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL15091079 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL24835038 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
Liquiritin SCHEMBL13931703 0.94 TRPA1 (1.00) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL10926327 0.92 TRPA1 (0.79) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL27939664 0.92 TRPA1 (0.79) TRPA1P4HBTRPV1PTPN1SLCO2B1
SCHEMBL31504735 0.92 TRPA1 (0.79) TRPA1P4HBTRPV1PTPN1SLCO2B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO claimed
CN-113671091-B Method for detecting blood-entering chemical components of four ministerial cough-relieving particles 西藏藏医药大学 2023-08-01 — — CN claimed
CN-115901978-A Detection method of traditional Chinese medicine composition 山东新时代药业有限公司 2023-04-04 — — CN claimed
CN-115721671-A Method for extracting and separating effective components of liquorice root in full-industrial-chain cooperation manner 李玉山 2023-03-03 — — CN claimed
CN-115015423-A Method for measuring contents of 17 chemical components in peony and licorice decoction 神威药业集团有限公司 2022-09-06 — — CN claimed
CN-114791471-A A pharmaceutical composition containing 'body pain dispelling blood stasis decoction' and its fingerprint detection method 漳州片仔癀药业股份有限公司 2022-07-26 — — CN claimed
CN-110568098-B Method for measuring concentration of apiose neoliquiritin in blood plasma 张家港市中医医院 2022-06-24 — — CN claimed
CN-114392263-A Glycyrrhiza neoside hair loss prevention and hair growth promotion composition and preparation method thereof 亿利耐雀生物科技有限公司 2022-04-26 — — CN claimed
CN-111624271-B Liquid chromatography method for detecting corresponding substance of peony and licorice decoction, standard fingerprint spectrum and application 厦门中药厂有限公司 2022-03-18 — — CN claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 — — US disclosed
US-20250177465-A1 TRADITIONAL CHINESE MEDICINE COMPOSITION AND PREPARATION METHOD AND APPLICATION THEREOF MEDONCARE PHARMACEUTICAL CO., LTD (CN) 2025-06-05 — — US disclosed
US-20250177426-A1 METHODS AND COMPOSITIONS FOR TREATING DEMENTIA Cognitive Synergy Corporation (US) 2025-06-05 — — US disclosed
US-20250177426-A1 METHODS AND COMPOSITIONS FOR TREATING DEMENTIA Cognitive Synergy Corporation (US) 2025-06-05 — — US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 — — US disclosed
CN-114392263-A Glycyrrhiza neoside hair loss prevention and hair growth promotion composition and preparation method thereof 亿利耐雀生物科技有限公司 2022-04-26 — — CN disclosed
CN-113413439-B Traditional Chinese medicine formula for treating Alzheimer's disease and preparation method of compound preparation of traditional Chinese medicine formula 中山创天生物科技有限公司 2022-03-29 — — CN disclosed
CN-111624271-B Liquid chromatography method for detecting corresponding substance of peony and licorice decoction, standard fingerprint spectrum and application 厦门中药厂有限公司 2022-03-18 — — CN disclosed
CN-216063669-U Liquorice draws processing rubbing crusher 新疆富沃药业有限公司 2022-03-18 — — CN disclosed
CN-109106877-B Traditional Chinese medicine composition for preventing and treating mastitis caused by excessive heat evil of women in lactation period, preparation method and pharmaceutical preparation thereof 河北中医学院 2022-02-01 — — CN disclosed
CN-113968938-A Method for preparing plant growth-promoting super absorbent resin from decoction dregs of four-monarch decoction 山东第一医科大学(山东省医学科学院) 2022-01-25 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO TRPA1 4582/4885P4HB 1596/4885TRPV1 4665/4885
US-20250177426-A1 METHODS AND COMPOSITIONS FOR TREATING DEMENTIA PSEN2, PSEN1, PYGB TRPA1 4859/4885P4HB 1707/4885TRPV1 4864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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