Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.62 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.62 |
| ▸ | CETP | P11597 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | UGCG | Q16739 | 2/20 | 0.61 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115606 | 1.00 | DEGS1 (0.63) | DEGS1ALDH1A1ASAH1ACER2CETP | |
| SCHEMBL8341808 | 0.93 | ALDH1A1 (0.71) | DEGS1ALDH1A1ASAH1ACER2MEN1 | |
| SCHEMBL7773484 | 0.93 | ALDH1A1 (0.71) | DEGS1ALDH1A1ASAH1ACER2MEN1 | |
| SCHEMBL7773486 | 0.93 | ALDH1A1 (0.71) | DEGS1ALDH1A1ASAH1ACER2MEN1 | |
| SCHEMBL12435699 | 0.86 | ASAH1 (0.85) | ALDH1A1ASAH1ACER2UGCGCERT1 | |
| SCHEMBL19328599 | 0.85 | ASAH2 (0.58) | DEGS1ALDH1A1CETPMEN1KMT2A | |
| SCHEMBL19352897 | 0.85 | ASAH2 (0.58) | DEGS1ALDH1A1CETPMEN1KMT2A | |
| SCHEMBL19342491 | 0.85 | ASAH2 (0.58) | DEGS1ALDH1A1CETPMEN1KMT2A | |
| SCHEMBL19342489 | 0.85 | ASAH2 (0.58) | DEGS1ALDH1A1CETPMEN1KMT2A | |
| SCHEMBL19352747 | 0.84 | ASAH2 (0.57) | DEGS1ALDH1A1CETPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230125-A1 | Small Molecule Allosteric Modulators of Serotonin (5-HT) 5-HT2C and 5-HT2A Receptors | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2025-07-17 | — | — | US | disclosed |
| EP-4504164-A1 | SMALL MOLECULE ALLOSTERIC MODULATORS OF THE SEROTONIN (5-HT) 5-HT2C AND 5-HT2A RECEPTORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023191951-A1 | SMALL MOLECULE ALLOSTERIC MODULATORS OF THE SEROTONIN (5-HT) 5-HT2C AND 5-HT2A RECEPTORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250230125-A1 | Small Molecule Allosteric Modulators of Serotonin (5-HT) 5-HT2C and 5-HT2A Receptors | HTR2C, HTR2A, HTR5A | DEGS1 2238/4885ALDH1A1 3449/4885ASAH1 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.