Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608324 | 0.78 | ALDH1A1 (0.34) | PDE1BPDE1APDE1CPDE4ATSHR | |
| SCHEMBL2612352 | 0.67 | PDE1B (0.43) | PDE1BPDE1APDE1CPDE4A | |
| SCHEMBL15943433 | 0.61 | PDE4A (0.39) | PDE1BPDE1APDE1CPDE4ATSHR | |
| SCHEMBL679839 | 0.60 | PRKDC (0.35) | PDE1BPDE1APDE1CPDE4ATSHR | |
| SCHEMBL16186217 | 0.59 | ALDH1A1 (0.35) | — | |
| SCHEMBL194043 | 0.59 | PDE1B (0.58) | PDE1BPDE1APDE1CPDE4A | |
| SCHEMBL193817 | 0.58 | PDE1B (0.57) | PDE1BPDE1APDE1CPDE4A | |
| SCHEMBL6762103 | 0.51 | CHRM2 (0.38) | — | |
| SCHEMBL18217957 | 0.51 | KMT2A (0.49) | — | |
| SCHEMBL18217853 | 0.51 | KMT2A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094966-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094966-A1 | ORGANIC COMPOUNDS | TPMT, CYP4X1, P2RX4 | PDE1B 4847/4885PDE1A 4868/4885PDE1C 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.