Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | PTPRF | P10586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546467 | 1.00 | AR (0.32) | ARP2RX3AKT1PTPRF | |
| SCHEMBL26123423 | 0.84 | ACHE (0.33) | AKT1 | |
| SCHEMBL22345863 | 0.82 | PTPRF (0.36) | ARPTPRF | |
| SCHEMBL20168433 | 0.81 | AKT1 (0.45) | AKT1 | |
| SCHEMBL26123929 | 0.81 | AKT1 (0.34) | P2RX3AKT1 | |
| SCHEMBL24329423 | 0.79 | — | — | |
| SCHEMBL21617656 | 0.79 | — | — | |
| SCHEMBL29582879 | 0.79 | — | — | |
| SCHEMBL26921579 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL26126323 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |