SCHEMBL26123750

SCHEMBL26123750

O=C(Nc1ccn([C@@H]2O[C@](CF)(COCc3ccccc3)[C@@H](OCc3ccccc3)[C@H]2O)c(=O)n1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 9/20 0.48
P2RY14 Q15391 2/20 0.48
NT5E P21589 1/20 0.48
ABL1 P00519 1/20 0.44
RIN1 Q13671 1/20 0.44
POLB P06746 1/20 0.42
P2RY2 P41231 4/20 0.40
P2RY4 P51582 4/20 0.40
ST6GAL1 P15907 5/20 0.39
P2RY12 Q9H244 1/20 0.38
USP30 Q70CQ3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2156785 0.93 P2RY6 (0.49) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26122701 0.88 P2RY6 (0.42) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26122705 0.88 P2RY6 (0.42) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26124477 0.87 P2RY6 (0.49) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26119053 0.87 P2RY6 (0.49) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26122341 0.85 P2RY6 (0.40) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26125589 0.83 ABL1 (0.51) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL1096958 0.80 P2RY6 (0.42) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL13607352 0.80 P2RY6 (0.44) P2RY6P2RY14NT5EABL1RIN1
SCHEMBL1096917 0.79 ABL1 (0.47) P2RY6P2RY14NT5EABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS INC (US) 2025-07-03 US disclosed
WO-2023192499-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS, INC. (US) 2023-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER UNG, OGG1, NTPCR P2RY6 2391/4885P2RY14 2970/4885NT5E 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.