SCHEMBL13607352

CC(C)(C)[Si](OC[C@]1(CO)O[C@@H](n2ccc(NC(=O)c3ccccc3)nc2=O)[C@@H](O)C1OCc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY6	Q15077	10/20	0.44

▸	P2RY14	Q15391	2/20	0.44

▸	NT5E	P21589	1/20	0.44

▸	ABL1	P00519	1/20	0.41

▸	RIN1	Q13671	1/20	0.41

▸	POLB	P06746	1/20	0.40

▸	P2RY2	P41231	5/20	0.37

▸	P2RY4	P51582	5/20	0.37

▸	ST6GAL1	P15907	4/20	0.35

▸	P2RY12	Q9H244	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2156785	0.87	P2RY6 (0.49)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL13607348	0.84	P2RY6 (0.38)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26123750	0.80	P2RY6 (0.48)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26124477	0.80	P2RY6 (0.49)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL26119053	0.80	P2RY6 (0.49)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL13615887	0.76	P2RY6 (0.43)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL13607353	0.75	ABL1 (0.38)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL20393996	0.74	NT5E (0.38)	P2RY6P2RY14NT5EP2RY2P2RY4
SCHEMBL20393999	0.74	NT5E (0.38)	P2RY6P2RY14NT5EP2RY2P2RY4
SCHEMBL26122578	0.74	ABL1 (0.43)	P2RY6P2RY14NT5EABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7615619-B2	Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof	TAKESHI IMANISHI (JP)	2009-11-10	—	—	US	disclosed