Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26123763 | 0.82 | ALDH1A1 (0.67) | ALDH1A1POLBHIF1ACYP2C9SMN1; SMN2 | |
| SCHEMBL25309479 | 0.79 | NPC1 (0.51) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22031540 | 0.79 | ALDH1A1 (0.49) | ALDH1A1POLBCYP2C9SMN1; SMN2TSHR | |
| SCHEMBL30632968 | 0.79 | ALDH1A1 (0.72) | ALDH1A1POLBHIF1ACYP2C9SMN1; SMN2 | |
| SCHEMBL30535966 | 0.77 | KMT2A (0.57) | ALDH1A1POLBSMN1; SMN2TSHRMEN1 | |
| SCHEMBL28864240 | 0.77 | ALDH1A1 (0.76) | ALDH1A1POLBHIF1ACYP2C9SMN1; SMN2 | |
| SCHEMBL19028140 | 0.76 | ALDH1A1 (0.46) | ALDH1A1POLBCYP2C9SMN1; SMN2TSHR | |
| SCHEMBL22031547 | 0.76 | ALDH1A1 (0.53) | ALDH1A1POLBSMN1; SMN2TSHRMEN1 | |
| SCHEMBL25268457 | 0.76 | NPC1 (0.55) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22031717 | 0.75 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185920-A1 | FAK DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BERRYBIO (SHANGHAI) LIMITED (CN) | 2023-10-05 | — | — | WO | disclosed |