Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632968 | 0.96 | ALDH1A1 (0.72) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28864240 | 0.95 | ALDH1A1 (0.76) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7361067 | 0.86 | ALDH1A1 (0.53) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28864238 | 0.84 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL26123765 | 0.82 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30480290 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3077817 | 0.81 | SMN1; SMN2 (0.72) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30488786 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31596236 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22031542 | 0.78 | ALDH1A1 (0.72) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185920-A1 | FAK DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BERRYBIO (SHANGHAI) LIMITED (CN) | 2023-10-05 | — | — | WO | disclosed |