Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831682 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL24910261 | 0.92 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29832043 | 0.92 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29831538 | 0.90 | CYP11B1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL26125533 | 0.90 | CYP11B1 (0.44) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29831799 | 0.84 | CYP11B1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL24909994 | 0.84 | CYP11B1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29832722 | 0.83 | PDGFRB (0.48) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL26122111 | 0.83 | PDGFRB (0.48) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL24686227 | 0.81 | CYP11B1 (0.46) | SMN1; SMN2MAPTCYP11B1HPRT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240049595-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| EP-4257585-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2023-10-11 | — | — | EP | disclosed |
| EP-4257585-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2023-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240049595-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | LAGE3, EED, EZH1 | NPC1 2299/4885RAB9A 1592/4885SMN1; SMN2 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.