Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24909994 | 1.00 | CYP11B1 (0.40) | CYP11B1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL29832043 | 0.85 | NPC1 (0.52) | CYP11B1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL24910261 | 0.85 | NPC1 (0.52) | CYP11B1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL23945065 | 0.84 | CYP11B1 (0.43) | CYP11B1NPC1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL29831682 | 0.84 | NPC1 (0.45) | CYP11B1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL26124152 | 0.84 | NPC1 (0.45) | CYP11B1NPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL15501317 | 0.84 | KMT2A (0.41) | CYP11B1NPC1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL22141168 | 0.82 | AHR (0.49) | CYP11B1NPC1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL23283873 | 0.80 | CHEK2 (0.37) | CYP11B1NPC1RAB9ASMN1; SMN2HCRTR1 | |
| SCHEMBL12037058 | 0.80 | ESR1 (0.42) | CYP11B1HCRTR1AHRMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240049595-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| EP-4257585-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-116507612-A | Heterocyclic compound, organic electroluminescent element, and electronic device | 保土谷化学工业株式会社 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022118910-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE | 保土谷化学工業株式会社 | 2022-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240049595-A1 | HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | LAGE3, EED, EZH1 | CYP11B1 4152/4885NPC1 2299/4885RAB9A 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.