SCHEMBL261254

SCHEMBL261254

CC(C)[C@@H](C)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4CCCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 7/20 0.70
▸ EPHA2 P29317 3/20 0.70
▸ HSD17B10 Q99714 3/20 0.70
▸ TDP1 Q9NUW8 3/20 0.70
▸ AKR1B10 O60218 2/20 0.70
▸ AKR1B1 P15121 2/20 0.70
▸ LMNA P02545 2/20 0.70
▸ EFNA1 P20827 1/20 0.70
▸ PSEN1 P49768 1/20 0.70
▸ PSEN2 P49810 1/20 0.70
▸ APH1B Q8WW43 1/20 0.70
▸ NCSTN Q92542 1/20 0.70
▸ APH1A Q96BI3 1/20 0.70
▸ PSENEN Q9NZ42 1/20 0.70
▸ MEN1 O00255 1/20 0.70
▸ KMT2A Q03164 1/20 0.70
▸ CYP2D6 P10635 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ INPP5D Q92835 1/20 0.52
▸ CASP7 P55210 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4998524 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL7630863 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL28244107 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL7624552 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL7623866 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL7863453 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL7623813 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL14677573 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL7623815 1.00 GPBAR1 (0.70) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL28088042 0.93 EPHA2 (0.67) GPBAR1EPHA2HSD17B10TDP1AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-25 — — US claimed
EP-3571264-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-11-24 — — EP claimed
CN-109134573-B Ergostane steroid compound, preparation method and application thereof 中国科学院上海药物研究所 2021-03-23 — — CN claimed
WO-2018134392-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-07-26 — — WO claimed
US-20170226150-A1 TRITERPENOID COMPOSITION OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF KAOHSIUNG MEDICAL UNIVERSITY (TW) 2017-08-10 — — US claimed
US-20160318972-A1 PREPARATION METHOD AND ANALYTIC METHOD FOR THE EXTRACT OF ANTRODIA CINNAMOMEA Wu, Yang-Chang (TW) 2016-11-03 — — US claimed
CN-104932032-A Discrimination method for charging period of underground biodegradation heavy oil reservoir UNIV CHINA PETROLEUM 2015-09-23 — — CN claimed
CN-104673676-A Harmful mycogone perniciosa and ergot sterane type triterpenoid prepared by fermentation as well as method TIANJIN INST IND BIOTECHNOLOGY CAS 2015-06-03 — — CN claimed
CN-104359933-A Triterpenoid composition of antrodia cinnamomea fruiting body, preparation and analysis method UNIV KAOHSIUNG MEDICAL 2015-02-18 — — CN claimed
US-20120190871-A1 TRITERPENOID COMPOSITION OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF KAOHSIUNG MEDICAL UNIVERSITY (TW) 2012-07-26 — — US claimed
US-20120087872-A1 Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof FOAMIX LTD. (IL) 2012-04-12 — — US claimed
WO-2010125470-A2 FOAMABLE VEHICLE AND PHARMACEUTICAL COMPOSITIONS COMPRISING APROTIC POLAR SOLVENTS AND USES THEREOF FOAMIX LTD. (IL) 2010-11-04 — — WO claimed
WO-2006045171-A2 PROCESS FOR OBTAINING DRY STEROIDS DERIVATIVE FROM ERGOSTANE Fundação Oswaldo Cruz (Fiocruz) (BR) 2006-05-04 — — WO claimed
US-20020007079-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 2002-01-17 — — US claimed
EP-1087988-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 2001-04-04 — — EP claimed
WO-1999067273-A1 MEIOSIS REGULATING COMPOUNDS NOVO NORDISK A/S (DK) 1999-12-29 — — WO claimed
JP-6305970-A — — None — — JP disclosed
EP-4401740-B1 USE OF TERPENOIDS IN THE TREATMENT OF MASTOCYTOMA ARJIL BIOTECH HOLDING COMPANY LTD (TW) 2026-04-01 — — EP disclosed
US-3998859-A Introducing Δ11 unsaturation into steroid compounds EASTMAN KODAK COMPANY (US) 1976-12-21 — — US disclosed
US-3931167-A Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein SCHERING CORPORATION (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007079-A1 MEIOSIS REGULATING COMPOUNDS CYP11A1, NR5A1, MNS1 GPBAR1 657/4885EPHA2 3823/4885HSD17B10 69/4885
US-20170226150-A1 TRITERPENOID COMPOSITION OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF CYP51A1, LSS, ERG28 GPBAR1 2072/4885EPHA2 3987/4885HSD17B10 139/4885
US-20210367155-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES EPB41, EPB41L2, MCM4 GPBAR1 2998/4885EPHA2 751/4885HSD17B10 2458/4885
US-20120190871-A1 TRITERPENOID COMPOSITION OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF CYP51A1, LSS, ERG28 GPBAR1 2072/4885EPHA2 3987/4885HSD17B10 139/4885
US-20160318972-A1 PREPARATION METHOD AND ANALYTIC METHOD FOR THE EXTRACT OF ANTRODIA CINNAMOMEA CYP51A1, LSS, ERG28 GPBAR1 2007/4885EPHA2 4741/4885HSD17B10 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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