Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31232508 | 1.00 | GHSR (0.46) | GHSRCXCR5PPIAPPARGPPARD | |
| SCHEMBL26131390 | 0.89 | GHSR (0.46) | GHSRCXCR5PPIASMN1; SMN2SLC8A1 | |
| SCHEMBL31232655 | 0.89 | GHSR (0.46) | GHSRCXCR5PPIASMN1; SMN2SLC8A1 | |
| SCHEMBL26130271 | 0.88 | GHSR (0.41) | GHSRCXCR5PPIASMN1; SMN2NPC1 | |
| SCHEMBL26131738 | 0.88 | GHSR (0.45) | GHSRCXCR5PPIASMN1; SMN2SLC8A1 | |
| SCHEMBL31232474 | 0.88 | GHSR (0.45) | GHSRCXCR5PPIASMN1; SMN2SLC8A1 | |
| SCHEMBL26404186 | 0.88 | GHSR (0.45) | GHSRCXCR5PPIASCN9ASLC8A1 | |
| SCHEMBL26131037 | 0.87 | GHSR (0.41) | GHSRCXCR5PPIATSHRSMN1; SMN2 | |
| SCHEMBL31232645 | 0.87 | GHSR (0.46) | GHSRCXCR5PPIASMN1; SMN2BACE1 | |
| SCHEMBL26130898 | 0.87 | GHSR (0.46) | GHSRCXCR5PPIASMN1; SMN2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023190878-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | Ａｔｒａｎｓｅｎ Ｐｈａｒｍａ株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190878-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | Ａｔｒａｎｓｅｎ Ｐｈａｒｍａ株式会社 | 2023-10-05 | — | — | WO | disclosed |