Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26131390 | 0.93 | GHSR (0.46) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL31232655 | 0.93 | GHSR (0.46) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL31232474 | 0.92 | GHSR (0.45) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL26131738 | 0.92 | GHSR (0.45) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL31232477 | 0.90 | GHSR (0.44) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL26131961 | 0.90 | GHSR (0.44) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL26131037 | 0.90 | GHSR (0.41) | GHSRSMN1; SMN2CXCR5PPIA | |
| SCHEMBL31232645 | 0.89 | GHSR (0.46) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL26130898 | 0.89 | GHSR (0.46) | GHSRSMN1; SMN2CXCR5PPIAADAM17 | |
| SCHEMBL31232508 | 0.88 | GHSR (0.46) | GHSRSMN1; SMN2CXCR5PPIAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035339-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | ATRANSEN PHARMA LTD (JP) | 2026-02-05 | — | — | US | disclosed |
| EP-4501906-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | Atransen Pharma Ltd. (JP) | 2025-02-05 | — | — | EP | disclosed |
| CN-118974007-A | Tetrahydronaphthalene derivatives | 阿创森制药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023190878-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | Ａｔｒａｎｓｅｎ Ｐｈａｒｍａ株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023190878-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | Ａｔｒａｎｓｅｎ Ｐｈａｒｍａ株式会社 | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035339-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | LATS1, LATS2, BCAT1 | GHSR 2073/4885SMN1; SMN2 2485/4885CXCR5 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.