SCHEMBL26129202

SCHEMBL26129202

COC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2C(C)C)c(C#N)c1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 20/20 0.56
CYP3A4 P08684 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476809 1.00 AGTR2 (0.56) AGTR2CYP3A4
SCHEMBL26129211 0.92 AGTR2 (0.62) AGTR2CYP3A4
SCHEMBL31476810 0.92 AGTR2 (0.62) AGTR2CYP3A4
SCHEMBL31476813 0.90 AGTR2 (0.56) AGTR2CYP3A4
SCHEMBL26131018 0.90 AGTR2 (0.56) AGTR2CYP3A4
SCHEMBL26128916 0.90 AGTR2 (0.67) AGTR2CYP3A4
SCHEMBL26129204 0.89 AGTR2 (0.48) AGTR2CYP3A4
SCHEMBL25246205 0.89 AGTR2 (0.58) AGTR2CYP3A4
SCHEMBL29437893 0.89 AGTR2 (0.58) AGTR2CYP3A4
SCHEMBL26128286 0.87 AGTR2 (0.48) AGTR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116891464-A AT2R agonist 武汉人福创新药物研发中心有限公司 2023-10-17 CN disclosed
WO-2023193733-A1 AT2R AGONIST 武汉人福创新药物研发中心有限公司 2023-10-12 WO disclosed