Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129227 | 1.00 | CTSS (0.53) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL26120706 | 0.92 | CTSS (0.52) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL16119327 | 0.92 | CTSS (0.52) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL26573222 | 0.89 | CTSS (0.49) | CTSSCTSKAAK1KMT2AHDAC4 | |
| SCHEMBL24298421 | 0.85 | CTSK (0.64) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL3814592 | 0.85 | CTSK (0.68) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL952034 | 0.85 | CTSK (0.64) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL3819388 | 0.85 | CTSK (0.68) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL952036 | 0.85 | CTSK (0.64) | CTSSCTSKIDO1AAK1ACE | |
| SCHEMBL3814600 | 0.85 | CTSK (0.68) | CTSSCTSKIDO1AAK1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196429-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-12 | — | — | WO | disclosed |