Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | AURKA | O14965 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 3/20 | 0.43 |
| ▸ | TEK | Q02763 | 3/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702373 | 0.81 | KDM4E (0.49) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL30406925 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL28427722 | 0.80 | GAA (0.45) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL27159700 | 0.76 | DDR2 (0.47) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL30702328 | 0.76 | DDR2 (0.47) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL30702334 | 0.74 | KDR (0.40) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL28198407 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL5408253 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL5408247 | 0.72 | KDM4E (0.64) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL23924017 | 0.71 | PDGFRB (0.64) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023190709-A1 | LIPOSOME COMPOSITION AND LIPOSOME-CONTAINING PHARMACEUTICAL COMPOSITION | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2023-10-05 | — | — | WO | disclosed |