Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2703580 | 0.82 | MEN1 (0.33) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12225458 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16386234 | 0.71 | ALDH1A1 (0.32) | LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL813730 | 0.71 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL23087072 | 0.71 | ALDH1A1 (0.32) | LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL16383084 | 0.71 | ALDH1A1 (0.32) | LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL24555362 | 0.71 | — | — | |
| SCHEMBL16383085 | 0.71 | ALDH1A1 (0.32) | LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL16383088 | 0.71 | ALDH1A1 (0.32) | LMNAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11183974 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023193759-A1 | HPK1 ANTAGONISTS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-10-12 | — | — | WO | disclosed |