Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26132556 | 0.94 | MAPK1 (0.35) | MAPK1CHRNB2CHRNA4IKZF2 | |
| SCHEMBL26133128 | 0.89 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL26133400 | 0.88 | MAPK1 (0.38) | MAPK1CHRNB2CHRNA4IRAK4HDAC1 | |
| SCHEMBL26132546 | 0.87 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL26094442 | 0.86 | MAPK1 (0.33) | MAPK1CHRNB2CHRNA4HDAC1 | |
| SCHEMBL26133806 | 0.86 | MAPK1 (0.31) | MAPK1CHRNB2CHRNA4 | |
| SCHEMBL26133803 | 0.85 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL26090922 | 0.85 | HDAC1 (0.30) | HDAC1 | |
| SCHEMBL26133327 | 0.85 | CHRNB2 (0.33) | MAPK1CHRNB2CHRNA4HDAC1 | |
| SCHEMBL26133268 | 0.84 | MAPK1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | claimed |