Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26133563 | 1.00 | NOS3 (0.41) | NOS3NOS1NOS2OTCGRM8 | |
| SCHEMBL25360834 | 0.94 | NOS3 (0.40) | NOS3NOS1NOS2OTCGRM8 | |
| SCHEMBL25360824 | 0.94 | NOS3 (0.40) | NOS3NOS1NOS2OTCGRM8 | |
| SCHEMBL25841802 | 0.93 | GLP1R (0.43) | NOS3NOS1NOS2OTCNOD1 | |
| SCHEMBL31297097 | 0.90 | MEN1 (0.38) | CRBNKMT2ALTA4HNOD1GLP1R | |
| SCHEMBL30980666 | 0.88 | CRBN (0.37) | CRBNKMT2AGLP1RCA12CA1 | |
| SCHEMBL20871341 | 0.86 | NOS2 (0.43) | NOS3NOS1NOS2OTCCYP1A2 | |
| SCHEMBL24610028 | 0.85 | OTC (0.44) | NOS2OTCGRM8GRM6GRIN2D | |
| SCHEMBL15469244 | 0.85 | OTC (0.44) | NOS2OTCGRM8GRM6GRIN2D | |
| SCHEMBL24906687 | 0.83 | MEN1 (0.33) | CRBNKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069994-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-27 | — | — | WO | disclosed |