Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738593 | 0.76 | ALDH1A1 (0.44) | TRPM4NQO2ALDH1A1KDM4EMEN1 | |
| SCHEMBL29977359 | 0.74 | TRPM4 (0.33) | TRPM4NQO2ALDH1A1PTPN22HPGD | |
| Benzene SCHEMBL28903867 | 0.74 | ALDH1A1 (0.45) | TRPM4NQO2ALDH1A1MAPTKDM4E | |
| SCHEMBL20699536 | 0.73 | ALDH1A1 (0.39) | TRPM4NQO2ALDH1A1MAPTKDM4E | |
| SCHEMBL10528671 | 0.71 | NQO1 (0.55) | TRPM4NQO2ALDH1A1MAPTKDM4E | |
| SCHEMBL30393017 | 0.69 | PTPN22 (0.54) | ALDH1A1MAPTKDM4EPTPN22GAA | |
| SCHEMBL20529660 | 0.69 | PTPN22 (0.54) | ALDH1A1MAPTKDM4EPTPN22GAA | |
| SCHEMBL27860879 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Benzene SCHEMBL21836124 | 0.68 | PTPN22 (0.52) | ALDH1A1MAPTKDM4EKMT2APTPN22 | |
| SCHEMBL27780597 | 0.68 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023179629-A1 | SUBSTITUTED BRIDGED RING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-09-28 | — | — | WO | disclosed |