⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26141012 | 0.83 | — | — | |
| SCHEMBL26141010 | 0.82 | BACE1 (0.31) | — | |
| SCHEMBL26141014 | 0.75 | HPGD (0.33) | — | |
| SCHEMBL26141026 | 0.73 | — | — | |
| SCHEMBL23714630 | 0.63 | PDK2 (0.33) | — | |
| SCHEMBL23705900 | 0.62 | BACE1 (0.33) | — | |
| SCHEMBL16265134 | 0.61 | PIK3CD (0.30) | — | |
| SCHEMBL25496620 | 0.61 | — | — | |
| SCHEMBL23706166 | 0.60 | PNMT (0.36) | — | |
| SCHEMBL26141017 | 0.60 | HPGD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145003-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |