Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26141017 | 0.81 | HPGD (0.37) | HPGDGFERHSD17B10PDK2 | |
| SCHEMBL23706166 | 0.78 | PNMT (0.36) | — | |
| SCHEMBL26141026 | 0.77 | — | — | |
| SCHEMBL26141011 | 0.75 | — | — | |
| SCHEMBL25496606 | 0.75 | PDK2 (0.33) | HPGDGFERHSD17B10PDK2 | |
| SCHEMBL25496618 | 0.75 | HPGD (0.37) | HPGDGFERHSD17B10PDK2 | |
| SCHEMBL26141015 | 0.75 | PDK2 (0.40) | HPGDGFERHSD17B10PDK2 | |
| SCHEMBL23705883 | 0.74 | CA12 (0.39) | — | |
| SCHEMBL23705881 | 0.74 | CA12 (0.39) | — | |
| SCHEMBL23706069 | 0.74 | CA12 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145003-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145003-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | HPGD 3705/4885GFER 4482/4885HSD17B10 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.