Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.78 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.65 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.65 |
| ▸ | BRD2 | P25440 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848894 | 0.88 | BRD4 (1.00) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL16650880 | 0.88 | BRD4 (1.00) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL26142004 | 0.82 | BRD4 (0.68) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL27263485 | 0.82 | BRD4 (0.68) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL24941911 | 0.81 | BRD9 (0.64) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL26142003 | 0.81 | BRD4 (0.67) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL3103150 | 0.81 | BRD4 (0.72) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL31589737 | 0.79 | BRD4 (0.64) | BRD4BRD9 | |
| SCHEMBL30032023 | 0.79 | BRD4 (0.64) | BRD4BRD9BRD7BRD2 | |
| SCHEMBL23783259 | 0.79 | BRD4 (0.64) | BRD4BRD9BRD7BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2024-02-29 | — | — | US | disclosed |
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-10-19 | — | — | US | disclosed |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331722-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | BRD4 42/4885BRD9 290/4885BRD7 149/4885 |
| US-20230142883-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | BRD4 42/4885BRD9 290/4885BRD7 149/4885 |
| US-20240067642-A1 | COMPOUNDS AND USES THEREOF | VHL, TFEB, BECN1 | BRD4 42/4885BRD9 290/4885BRD7 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.