Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27278154 | 0.95 | HTT (0.68) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL2614412 | 0.90 | MEN1 (0.73) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL14221833 | 0.84 | MEN1 (0.69) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL17268215 | 0.84 | MEN1 (0.60) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL2614402 | 0.83 | LMNA (0.97) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL12893718 | 0.83 | MAPT (0.67) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL7750100 | 0.81 | LMNA (0.47) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL6870013 | 0.81 | MAPT (0.50) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL2614442 | 0.80 | KMT2A (0.56) | MAPTHTTMEN1LMNATHRB | |
| SCHEMBL7750107 | 0.80 | MAPT (0.46) | MAPTHTTMEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729276-B2 | Cyanine compound for labeling biomolecule and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-05-20 | — | — | US | disclosed |
| US-20120095187-A1 | NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF | DKC CORPORATION (KR) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095187-A1 | NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF | MRPL21, MB, CCNB1 | MAPT 2264/4885HTT 3119/4885MEN1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.