Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733305 | 0.90 | MEN1 (0.40) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL1656985 | 0.88 | MEN1 (0.42) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL7750100 | 0.88 | LMNA (0.47) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL5271477 | 0.87 | MEN1 (0.41) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL3859355 | 0.87 | MEN1 (0.41) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL721215 | 0.87 | MEN1 (0.41) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL5271474 | 0.87 | MEN1 (0.41) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL30148940 | 0.87 | MEN1 (0.41) | MAPTMEN1LMNATHRBHTT | |
| Bromide SCHEMBL6537215 | 0.87 | MEN1 (0.41) | MAPTMEN1LMNATHRBHTT | |
| SCHEMBL1367336 | 0.86 | LMNA (0.61) | MAPTMEN1LMNATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120164635-A1 | LARGE STOKE SHIFT NIR DYES | VANDERBILT UNIVERSITY | 2012-06-28 | — | — | US | disclosed |
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120164635-A1 | LARGE STOKE SHIFT NIR DYES | SLC7A5, SLC43A1, SPIN3 | MAPT 2412/4885MEN1 608/4885LMNA 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.