SCHEMBL26145

SCHEMBL26145

O=[C]NC1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL245390 1.00 ALDH1A1 (0.45)
SCHEMBL2112447 1.00 ALDH1A1 (0.45)
SCHEMBL2109467 1.00 ALDH1A1 (0.45)
SCHEMBL1678761 1.00 ALDH1A1 (0.45)
SCHEMBL9206593 1.00 ALDH1A1 (0.45)
SCHEMBL26241 0.97
SCHEMBL115508 0.91
SCHEMBL24679 0.84
SCHEMBL5639673 0.76 TSHR (0.38)
SCHEMBL33021 0.75 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4511 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-117794923-A Benzodioxane compound, and preparation method and application thereof 南京红云生物科技有限公司 2024-03-29 CN claimed
US-20240018140-A1 MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-01-18 US claimed
US-20240009169-A9 PPARG Modulators for the Treatment of Osteoporosis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2024-01-11 US claimed
US-20230348387-A1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC. (CA) 2023-11-02 US claimed
US-20230310428-A1 EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF Hongyun Biotech Co., Ltd. (CN) 2023-10-05 US claimed
EP-4213843-A2 MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Merck Sharp & Dohme LLC (US) 2023-07-26 EP claimed
CN-114621137-B Difluorobutoxy method of N-aryl-N-hydroxylamine compound participated in tetrahydrofuran 浙江工业大学 2023-07-14 CN claimed
US-20230212147-A1 ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Hongyun Biotech Co., Ltd. (CN) 2023-07-06 US claimed
EP-0034326-B1 CHIRAL POLYSILOXANES, PROCESS FOR THEIR PREPARATION AND THEIR USE Bayer, Ernst, Prof. Dr. (DE) 1984-07-25 EP claimed
EP-0033984-B1 NEW SULPHONYL COMPOUNDS, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS APHICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1984-06-06 EP claimed
US-4387206-A CHROMATOGRAPHY BAYER ERNST (DE) 1983-06-07 US claimed
US-4379157-A Sulphonyl compounds, method of preparing the new compounds, as well as aphicidal compositions on the basis of the new compounds DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1983-04-05 US claimed
EP-0072348-A2 Phenoxyphenyl-aminocarboxylic-acid derivatives, their preparation, compositions containing them and their use CIBA-GEIGY AG (CH) 1983-02-16 EP claimed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 EP claimed
US-4111933-A PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION BAYER AKTIENGESELLSCHAFT (DE) 1978-09-05 US claimed
US-4041072-A PSYCHOTROPIC AGENTS DELALANDE S. A. (FR) 1977-08-09 US claimed
US-3991189-A Microbiocidal methods and compositions using substituted 1,2,4-triazine-1,4-di-N-oxide derivatives BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed
US-3956326-A AZO DYE BASF AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed