Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764612 | 0.81 | CKS1B (0.56) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL25178650 | 0.79 | ACHE (0.53) | ACHECKS1BSKP1SKP2STS | |
| SCHEMBL25419563 | 0.79 | CKS1B (0.49) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL17373792 | 0.78 | CKS1B (0.46) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL14990872 | 0.78 | CKS1B (0.46) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL26146347 | 0.77 | CKS1B (0.47) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL26094150 | 0.77 | CKS1B (0.43) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL2881674 | 0.77 | GPR119 (0.61) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL713180 | 0.75 | GPR119 (0.61) | ACHECKS1BSKP1SKP2GPR119 | |
| SCHEMBL25172068 | 0.74 | GPR119 (0.56) | ACHECKS1BSKP1SKP2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081923-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Frequency Therapeutics, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |