Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12579075 | 0.90 | MAPT (0.55) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL28466842 | 0.88 | MAPT (0.57) | MAPTRAB9ALMNAHPGDTSHR | |
| SCHEMBL9335265 | 0.86 | MAPT (0.52) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL12924442 | 0.86 | ALDH1A1 (0.55) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL9483425 | 0.86 | ALDH1A1 (0.55) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL19892095 | 0.86 | ALDH1A1 (0.55) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL14727179 | 0.86 | ALDH1A1 (0.55) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL217123 | 0.86 | ALDH1A1 (0.55) | MAPTPKMRAB9ALMNAMEN1 | |
| SCHEMBL7853742 | 0.85 | PKM (0.60) | MAPTPKMLMNAMEN1KMT2A | |
| SCHEMBL17933392 | 0.85 | PKM (0.60) | MAPTPKMLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728234-B1 | RADIOLABELED COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2025-05-14 | — | — | EP | disclosed |
| US-11541132-B2 | Radiolabeled compounds | HOFFMANN-LA ROCHE INC. (US) | 2023-01-03 | — | — | US | disclosed |
| EP-3728234-A1 | RADIOLABELED COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2020-10-28 | — | — | EP | disclosed |
| US-20200316232-A1 | RADIOLABELED COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2020-10-08 | — | — | US | disclosed |
| CN-111511732-A | Radiolabelled compounds | 豪夫迈·罗氏有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-9057018-B2 | Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and polymer thereof | JNC CORPORATION (JP) | 2015-06-16 | — | — | US | disclosed |
| US-8623476-B2 | Polarizing element and method of producing the same | FUJIFILM CORPORATION (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20130169896-A1 | STEREO IMAGE PRINT AND METHOD OF PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2013-07-04 | — | — | US | disclosed |
| US-8477423-B2 | Method of producing a patterned birefringent product | FUJIFILM CORPORATION (JP) | 2013-07-02 | — | — | US | disclosed |
| US-8477275-B2 | Optical film and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2013-07-02 | — | — | US | disclosed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |
| US-4593119-A | ADRENERGIC BLOCKING AGENTS OF SHORT DURARION | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| US-4387103-A | SHORT ACTING BETA BLOCKING AGENTS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0065542-A4 | COMPOUNDS SUITABLE FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1983-04-25 | — | — | EP | disclosed |
| EP-0065542-A1 | COMPOUNDS SUITABLE FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1982-12-01 | — | — | EP | disclosed |
| WO-1982001869-A1 | METHOD FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS | AMERICAN HOSPITAL SUPPLY CORP (US) | 1982-06-10 | — | — | WO | disclosed |
| EP-0053435-A1 | Compounds suitable for treatment or prophylaxis of cardiac disorders | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1982-06-09 | — | — | EP | disclosed |
| US-4070415-A | Thermoplastic molding compositions on the basis of polyoxymethylenes | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-24 | — | — | US | disclosed |
| US-3980734-A | Thermoplastic moulding compositions based on poly (oxymethylene) | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3961071-A | CARDIOVASCULAR DISORDERS, 1-PHENOXY-2-HYDROXY-3-TERT-BUTYLAMINO PROPANES | BOEHRINGER INGELHEIM GMBH (DT) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541132-B2 | Radiolabeled compounds | SNCA, APP, BACE1 | MAPT 16/4885PKM 3491/4885RAB9A 163/4885 |
| US-20200316232-A1 | RADIOLABELED COMPOUNDS | SNCA, APP, BACE1 | MAPT 17/4885PKM 3636/4885RAB9A 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.