SCHEMBL2614749

SCHEMBL2614749

CC(=O)CCc1nc(-c2cccc(-c3noc(C)n3)c2)no1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.61
MAPK1 P28482 3/20 0.56
HTT P42858 1/20 0.56
TSHR P16473 1/20 0.54
KMT2A Q03164 1/20 0.54
GLA P06280 1/20 0.52
ALDH1A1 P00352 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HPGD P15428 1/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11983369 0.84 ALDH1A1 (0.69) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL11953070 0.83 L3MBTL1 (0.52) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL13130279 0.82 L3MBTL1 (0.51) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL16367708 0.82 MAPK1 (0.56) MAPK1HTTTSHRKMT2AALDH1A1
SCHEMBL27383742 0.81 L3MBTL1 (0.63) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL13167065 0.80 L3MBTL1 (0.67) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL25165865 0.80 L3MBTL1 (0.49) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL13130273 0.79 L3MBTL1 (0.48) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL13130285 0.79 L3MBTL1 (0.48) L3MBTL1MAPK1HTTTSHRKMT2A
SCHEMBL13130263 0.79 L3MBTL1 (0.65) L3MBTL1MAPK1TSHRKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8920889-B2 Optical film, polarizing plate, and image-forming display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8920889-B2 Optical film, polarizing plate, and image-forming display device FUJIFILM CORPORATION (JP) 2014-12-30 US disclosed
US-8889236-B2 2014-11-18 US disclosed
US-8889236-B2 2014-11-18 US disclosed
US-20130222910-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE-FORMING DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-20130222910-A1 OPTICAL FILM, POLARIZING PLATE, AND IMAGE-FORMING DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-29 US disclosed
US-8477275-B2 Optical film and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-8477275-B2 Optical film and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20120092594-A1 OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-20120092594-A1 OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed