SCHEMBL261504

SCHEMBL261504

COc1cccc(C(N)=O)c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
KDM4E B2RXH2 2/20 0.56
NPC1 O15118 5/20 0.54
RAB9A P51151 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
TP53 P04637 2/20 0.53
HPGD P15428 2/20 0.53
KMT2A Q03164 4/20 0.52
GAA P10253 2/20 0.52
HSD17B10 Q99714 1/20 0.52
MEN1 O00255 2/20 0.51
POLB P06746 3/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
CNR2 P34972 1/20 0.49
NFE2L2 Q16236 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16654449 0.98 MAPT (0.54) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL3395132 0.88 PARP1 (0.47) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL27511872 0.87 KDM4E (0.46) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL5242291 0.84 PARP1 (0.51) MAPTKDM4ENPC1RAB9AHPGD
SCHEMBL4062441 0.84 PARP1 (0.54) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL3762150 0.84 RAB9A (0.55) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL341046 0.82 NPC1 (0.58) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL152563 0.82 MAPT (0.59) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL29603325 0.82 MAPT (0.59) MAPTKDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL6964175 0.82 RAB9A (0.58) MAPTKDM4ENPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115671286-B Stereocomplex for delivery of anticancer agents 田德扬 2023-12-08 CN claimed
CN-114643077-B Microporous gel polymer with photocatalytic activity and preparation method thereof 湖北大学 2023-09-26 CN claimed
EP-4168399-A1 COMPOUNDS AND THEIR USES AS MIF INHIBITORS Nanjing Immunophage Biotech Co., Ltd. (CN) 2023-04-26 EP claimed
CN-115671286-A Stereocomplex for delivery of anticancer agents 田德扬 2023-02-03 CN claimed
CN-113260653-B Stereocomplex for delivery of anticancer agents 田德扬 2022-11-04 CN claimed
CN-114643077-A Microporous polymer with photocatalytic activity and preparation method thereof 湖北大学 2022-06-21 CN claimed
WO-2021258272-A1 COMPOUNDS AND THEIR USES AS MIF INHIBITORS Nanjing Immunophage Biotech Co., Ltd. (CN) 2021-12-30 WO claimed
WO-2021253780-A1 ZINC OXIDE NANOMATERIAL AND PREPARATION METHOD THEREFOR, AND SEMICONDUCTOR DEVICE TCL科技集团股份有限公司 2021-12-23 WO claimed
CN-109071530-B Fused pyrimidine piperidine ring derivatives, and preparation method and application thereof 上海艾力斯医药科技股份有限公司 2021-08-17 CN claimed
CN-110642741-A Functionalized benzamide derivatives as antiviral agents against HBV infection 巴鲁克斯布隆伯格研究所 2020-01-03 CN claimed
JP-2004505977-A 2004-02-26 JP claimed
EP-1320531-A2 BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Pharmacia Italia S.p.A. (IT) 2003-06-25 EP claimed
WO-2003040096-A2 N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES ELAN PHARMACEUTICALS, INC. (US) 2003-05-15 WO claimed
WO-2003014090-A1 AMINO-PHTHALAZINONE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM PHARMACIA ITALIA S.P.A. (IT) 2003-02-20 WO claimed
WO-2003009850-A1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC. (US) 2003-02-06 WO claimed
EP-1155017-B1 [1,8] NAPHTHYRIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY SHIRE BIOCHEM INC (CA) 2003-01-15 EP claimed
WO-2002028353-A2 PHOSPHATE TRANSPORT INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-04-11 WO claimed
WO-2002012242-A2 BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PHARMACIA ITALIA S.P.A. (IT) 2002-02-14 WO claimed
EP-1124810-A1 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS PHARMACIA & UPJOHN S.p.A. (IT) 2001-08-22 EP claimed
WO-2000026202-A1 2-AMINO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS PHARMACIA & UPJOHN S.P.A. (IT) 2000-05-11 WO claimed