Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762150 | 0.86 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29603325 | 0.84 | MAPT (0.59) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL152563 | 0.84 | MAPT (0.59) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL341046 | 0.84 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29931828 | 0.84 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8528108 | 0.82 | KMT2A (0.59) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| Methyl 2,3-Dimethoxybenzoate SCHEMBL311487 | 0.82 | GAA (0.66) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL261504 | 0.82 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL3556531 | 0.82 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL341330 | 0.82 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | claimed |
| US-6268310-B1 | CONTROLLING WEEDS | NIPPON SODA CO., LTD. (JP) | 2001-07-31 | — | — | US | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | disclosed |