Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24708771 | 0.81 | LMNA (0.34) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL18431720 | 0.79 | — | — | |
| SCHEMBL20076861 | 0.75 | — | — | |
| SCHEMBL4565411 | 0.73 | CASP2 (0.47) | LMNAPOLBCNR1CNR2 | |
| SCHEMBL13636324 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5707324 | 0.71 | CASP2 (0.45) | LMNAPOLBCNR1CNR2 | |
| SCHEMBL19983262 | 0.70 | — | — | |
| SCHEMBL20606606 | 0.68 | LMNA (0.40) | LMNAPOLBCNR1CNR2SMN1; SMN2 | |
| SCHEMBL24689103 | 0.68 | LMNA (0.30) | LMNAPOLBCNR1CNR2 | |
| SCHEMBL12441250 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083210-A1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |