Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.84 |
| ▸ | HRH1 | P35367 | 2/20 | 0.84 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.84 |
| ▸ | DRD2 | P14416 | 3/20 | 0.74 |
| ▸ | DRD4 | P21917 | 3/20 | 0.74 |
| ▸ | DRD3 | P35462 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.74 |
| ▸ | HTR3B | O95264 | 1/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.74 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615365 | 1.00 | CHRM1 (0.84) | CHRM1HRH1PAK1DRD2DRD4 | |
| SCHEMBL21258026 | 0.88 | CHRM1 (0.65) | CHRM1HRH1PAK1DRD2DRD4 | |
| SCHEMBL9013860 | 0.86 | CHRM1 (1.00) | CHRM1HRH1PAK1DRD2DRD4 | |
| SCHEMBL3414200 | 0.86 | CHRM1 (0.74) | CHRM1HRH1PAK1DRD2DRD4 | |
| SCHEMBL21234807 | 0.86 | CHRM1 (0.78) | CHRM1HRH1PAK1DRD2DRD4 | |
| SCHEMBL7410410 | 0.86 | CHRM1 (0.73) | CHRM1HRH1PAK1DRD2DRD4 | |
| SCHEMBL141020 | 0.86 | DRD2 (1.00) | CHRM1HRH1DRD2DRD4DRD3 | |
| SCHEMBL29470861 | 0.86 | DRD2 (1.00) | CHRM1HRH1DRD2DRD4DRD3 | |
| Clozapine SCHEMBL20876213 | 0.85 | DRD2 (1.00) | CHRM1HRH1DRD2DRD4DRD3 | |
| Clozapine SCHEMBL5501558 | 0.85 | DRD2 (1.00) | CHRM1HRH1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | CHRM1 4388/4885HRH1 4629/4885PAK1 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.