Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157121 | 0.92 | DRD2 (0.51) | DRD2LMNAMAPTALDH1A1TSHR | |
| SCHEMBL26157324 | 0.86 | TSHR (0.44) | DRD2HRH3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL26157262 | 0.83 | ALDH1A1 (0.42) | DRD2HRH3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL24461261 | 0.81 | TSHR (0.41) | TP53MAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL26157117 | 0.80 | DRD2 (0.49) | DRD2TP53TSHRHTR1ADRD1 | |
| SCHEMBL26157095 | 0.79 | TSHR (0.44) | LMNATP53MAPTALDH1A1TSHR | |
| SCHEMBL24461258 | 0.79 | TSHR (0.44) | LMNATP53MAPTALDH1A1TSHR | |
| SCHEMBL24461260 | 0.79 | TSHR (0.44) | LMNATP53MAPTALDH1A1TSHR | |
| SCHEMBL26157322 | 0.77 | ALDH1A1 (0.39) | TP53MAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL24461815 | 0.77 | TSHR (0.44) | LMNATP53MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |