Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 8/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157094 | 0.90 | ACACB (0.43) | KDM4EACACBCYP2C19KMT2AUSP2 | |
| SCHEMBL24461253 | 0.90 | ACACB (0.43) | KDM4EACACBCYP2C19KMT2AUSP2 | |
| SCHEMBL26157131 | 0.87 | HRH3 (0.41) | HRH3ADRA1AKDM4ECYP2C19KMT2A | |
| SCHEMBL26157132 | 0.82 | SLC18A3 (0.36) | KDM4ECYP2C19JAK3BTKLCK | |
| SCHEMBL25109073 | 0.80 | JAK3 (0.34) | ACACBJAK3BTKLCK | |
| SCHEMBL25111181 | 0.80 | JAK3 (0.34) | ACACBJAK3BTKLCK | |
| SCHEMBL24511405 | 0.79 | JAK3 (0.34) | KDM4ECYP2C19JAK3BTKLCK | |
| SCHEMBL25475906 | 0.78 | ACACB (0.45) | ADRA1AKDM4EACACBCYP2C19KMT2A | |
| SCHEMBL25475903 | 0.78 | ACACB (0.45) | ADRA1AKDM4EACACBCYP2C19KMT2A | |
| SCHEMBL25604691 | 0.78 | ACACB (0.45) | ADRA1AKDM4EACACBCYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |