Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26157094 | 1.00 | ACACB (0.43) | ACACBKDM4ECYP2C19KMT2ASLC6A9 | |
| SCHEMBL26157130 | 0.90 | HRH3 (0.39) | ACACBKDM4ECYP2C19KMT2AUSP2 | |
| SCHEMBL25604691 | 0.87 | ACACB (0.45) | ACACBKDM4ECYP2C19KMT2ASLC6A9 | |
| SCHEMBL25475903 | 0.87 | ACACB (0.45) | ACACBKDM4ECYP2C19KMT2ASLC6A9 | |
| SCHEMBL25475906 | 0.87 | ACACB (0.45) | ACACBKDM4ECYP2C19KMT2ASLC6A9 | |
| SCHEMBL24461260 | 0.85 | TSHR (0.44) | ACACBKMT2AUSP2SMN1; SMN2GPR119 | |
| SCHEMBL26157095 | 0.85 | TSHR (0.44) | ACACBKMT2AUSP2SMN1; SMN2GPR119 | |
| SCHEMBL24461258 | 0.85 | TSHR (0.44) | ACACBKMT2AUSP2SMN1; SMN2GPR119 | |
| SCHEMBL26157322 | 0.80 | ALDH1A1 (0.39) | ACACBKDM4EKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26157319 | 0.80 | ADRA1A (0.52) | KDM4ECYP2C19KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109426-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2022-05-27 | — | — | WO | disclosed |