SCHEMBL26157195

SCHEMBL26157195

Cc1ccnc(OC2CC(OCC3CCN(C)CC3)C2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 3/20 0.38
HCRTR2 O43614 3/20 0.38
LOX P28300 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
CHRM2 P08172 2/20 0.37
CHRM1 P11229 2/20 0.37
PIK3CD O00329 1/20 0.37
CHRM3 P20309 1/20 0.37
HRH3 Q9Y5N1 1/20 0.36
LRRK2 Q5S007 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CRHR1 P34998 1/20 0.35
AXL P30530 1/20 0.35
TYRO3 Q06418 1/20 0.35
MERTK Q12866 1/20 0.35
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
NOS3 P29474 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL427054 0.82 HRH3 (0.44) HCRTR1HCRTR2HRH3MAOAMAOB
SCHEMBL427767 0.82 LRRK2 (0.48) HCRTR1HCRTR2LOXLOXL2PIK3CD
SCHEMBL23205103 0.81 TLR9 (0.38) HCRTR1HCRTR2LOXLOXL2PIK3CD
SCHEMBL23205104 0.81 TLR9 (0.38) HCRTR1HCRTR2LOXLOXL2PIK3CD
SCHEMBL26157155 0.80 TLR9 (0.41) HCRTR1HCRTR2LOXLOXL2PIK3CD
SCHEMBL426634 0.75 CTSL (0.41) HRH3CRHR1CCR1CCR5CCR8
SCHEMBL426645 0.74 HRH4 (0.44) CCR1CCR5CCR8NOS3NOS1
SCHEMBL26157127 0.73 HRH3 (0.39) HCRTR1HCRTR2LOXLOXL2HRH3
SCHEMBL26157126 0.73 HRH3 (0.39) HCRTR1HCRTR2LOXLOXL2HRH3
SCHEMBL16453455 0.73 LOX (0.53) HCRTR1HCRTR2LOXLOXL2LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023093728-A1 BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF 江苏先声药业有限公司 2023-06-01 WO disclosed