Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14043468 | 0.84 | ATM (0.50) | ATMPPARGPPARAPPARDCA1 | |
| SCHEMBL15854849 | 0.81 | CTSK (0.46) | CTSK | |
| SCHEMBL9544068 | 0.79 | PPARA (0.46) | ATMPPARGPPARAPPARDCTSK | |
| SCHEMBL9544071 | 0.79 | PPARA (0.46) | ATMPPARGPPARAPPARDCTSK | |
| SCHEMBL17905303 | 0.79 | EPHX2 (0.42) | ATMPPARGPPARAPPARDKLK5 | |
| SCHEMBL30496988 | 0.78 | ATM (0.48) | ATMPPARGPPARAPPARDCTSK | |
| SCHEMBL12806200 | 0.76 | CTSK (0.52) | ATMPPARGPPARACA1CA2 | |
| SCHEMBL27566993 | 0.75 | SYK (0.48) | ATMPPARGPPARAPPARDCTSK | |
| SCHEMBL2350194 | 0.74 | PPARA (0.51) | ATMPPARGPPARACA1CA2 | |
| SCHEMBL29401143 | 0.74 | PPARA (0.51) | ATMPPARGPPARACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140186378-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186378-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-03 | — | — | US | disclosed |
| US-8163290-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163290-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110086053-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086053-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-14 | — | — | US | disclosed |
| US-7923013-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923013-B2 | Glycolipids and analogues thereof as antigens for NKT cells | THE ROCKEFELLER UNIVERSITY (US) | 2011-04-12 | — | — | US | disclosed |
| US-20070238871-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2007-10-11 | — | — | US | disclosed |
| US-20070238871-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | THE ROCKEFELLER UNIVERSITY (US) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086053-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | CD69, KLRK1, PBK | ATM 3744/4885PPARG 993/4885PPARA 551/4885 |
| US-20140186378-A1 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS | CD69, KLRK1, PBK | ATM 3744/4885PPARG 993/4885PPARA 551/4885 |
| US-20070238871-A1 | Glycolipids And Analogues Thereof As Antigens For NKT Cells | CD69, KLRK1, PBK | ATM 3744/4885PPARG 993/4885PPARA 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.