Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544068 | 1.00 | PPARA (0.46) | PPARAPPARGPPARDAPPATM | |
| SCHEMBL7105936 | 0.86 | TSHR (0.55) | PPARAPPARGPPARDAPPATM | |
| SCHEMBL7105931 | 0.86 | TSHR (0.55) | PPARAPPARGPPARDAPPATM | |
| SCHEMBL30496988 | 0.83 | ATM (0.48) | PPARAPPARGPPARDATMTSHR | |
| SCHEMBL1926641 | 0.81 | KDM4E (0.37) | PPARAPPARGPPARDAPPATM | |
| SCHEMBL10809684 | 0.81 | SLC1A2 (0.55) | PPARAPPARGTSHRTP53ALDH1A1 | |
| SCHEMBL25076073 | 0.81 | SLC1A3 (0.44) | PPARAPPARGPPARDAPPATM | |
| SCHEMBL2615736 | 0.79 | ATM (0.43) | PPARAPPARGPPARDATMCTSK | |
| SCHEMBL16488743 | 0.78 | CTSK (0.47) | APPCTSKCTSSTRPA1 | |
| SCHEMBL14673227 | 0.78 | CTSK (0.47) | APPCTSKCTSSTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |