Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427991 | 0.86 | KCNH2 (0.39) | KCNH2CHRM1AKT1 | |
| SCHEMBL1198152 | 0.80 | — | — | |
| SCHEMBL6028304 | 0.79 | PARP1 (0.34) | GNAI3GNAO1GNAI1PARP1KHK | |
| SCHEMBL25090988 | 0.78 | HTR4 (0.34) | KCNH2CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL6629106 | 0.78 | KCNH2 (0.71) | KCNH2GNAI3GNAO1GNAI1RAD52 | |
| SCHEMBL26067204 | 0.77 | KDM1A (0.39) | GNAI3GNAO1GNAI1RAD52PARP1 | |
| SCHEMBL10177926 | 0.76 | CHRM2 (0.35) | GNAI3GNAO1GNAI1PARP1KHK | |
| SCHEMBL19723152 | 0.76 | KCNH2 (0.34) | KCNH2AKT1 | |
| SCHEMBL6269856 | 0.75 | GNAI3 (0.45) | GNAI3GNAO1GNAI1RAD52PARP1 | |
| SCHEMBL13874224 | 0.75 | KCNH2 (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093728-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2023-06-01 | — | — | WO | disclosed |