Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.82 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.80 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.62 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 9/20 | 0.56 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | EP300 | Q09472 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coptisine SCHEMBL156866 | 0.90 | IDO1 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL29931632 | 0.90 | IDO1 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL31392604 | 0.90 | IDO1 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL154528 | 0.89 | METTL3 (1.00) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL2441815 | 0.89 | IDO1 (0.98) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL8858972 | 0.84 | IDO1 (0.87) | IDO1METTL3METTL14ALDH1A1LMNA | |
| Coptisine SCHEMBL158088 | 0.81 | METTL3 (0.82) | IDO1METTL3METTL14ALDH1A1LMNA | |
| SCHEMBL26159291 | 0.80 | IDO1 (0.55) | IDO1METTL3METTL14ALDH1A1LMNA | |
| SCHEMBL25931816 | 0.79 | EP300 (0.88) | IDO1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| Coptisine SCHEMBL16279007 | 0.79 | METTL3 (0.79) | IDO1METTL3METTL14ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088319-A1 | MONTELUKAST BERBERINE QUATERNARY AMMONIUM SALT COMPOUND AND DOUBLE SALT COMPOSITION, AND SYNTHESIS METHOD THEREFOR AND USE THEREOF | 温州医科大学附属眼视光医院 | 2023-05-25 | — | — | WO | disclosed |