Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602763 | 0.87 | KMT2A (0.52) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL25022810 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL19026680 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL24835399 | 0.82 | KMT2A (0.42) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL14602770 | 0.82 | KMT2A (0.42) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL26668826 | 0.81 | MEN1 (0.48) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL17017539 | 0.80 | TSHR (0.38) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL18360428 | 0.80 | TSHR (0.38) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL19661876 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1USP2MEN1MAPT | |
| SCHEMBL24971342 | 0.79 | KMT2A (0.41) | KMT2AALDH1A1USP2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252030-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | Life Technologies Corporation (US) | 2012-10-04 | — | — | US | disclosed |
| US-8163897-B2 | 5-bromo-2′-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same | APPLIED BIOSYSTEMS, LLC (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110207920-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | Life Technologies Corporation (US) | 2011-08-25 | — | — | US | disclosed |
| US-7915392-B2 | 5-bromo-2′-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same | Life Technologies Corporation (US) | 2011-03-29 | — | — | US | disclosed |
| US-20090325158-A1 | 5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates and Nucleic Acid Probes and Methods of Making and Using the Same | APPLERA CORPORATION (US) | 2009-12-31 | — | — | US | disclosed |
| WO-2008157311-A2 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | APPLERA CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207920-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | DUT, PCNA, TK1 | KMT2A 3631/4885ALDH1A1 1607/4885USP2 1238/4885 |
| US-20090325158-A1 | 5-Bromo-2'-Deoxy-Uridine Labeled Nucleotide Triphosphates and Nucleic Acid Probes and Methods of Making and Using the Same | DUT, PCNA, TK1 | KMT2A 3631/4885ALDH1A1 1607/4885USP2 1238/4885 |
| US-20120252030-A1 | 5-BROMO-2'-DEOXY-URIDINE LABELED NUCLEOTIDE TRIPHOSPHATES AND NUCLEIC ACID PROBES AND METHODS OF MAKING AND USING THE SAME | DUT, PCNA, TK1 | KMT2A 3631/4885ALDH1A1 1607/4885USP2 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.