SCHEMBL26164145

SCHEMBL26164145

Nc1c(-c2ccccc2)cccc1-c1ccccc1-c1ccccc1-c1cccc([N+](=O)[O-])c1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAOA P21397 1/20 0.40
S100A4 P26447 2/20 0.40
PTPRC P08575 1/20 0.40
PSMD14 O00487 1/20 0.39
PRKACA P17612 1/20 0.39
CASP6 P55212 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565552 1.00 ALDH1A1 (0.56) ALDH1A1TDP1MEN1KMT2AMAOA
SCHEMBL26164174 0.88 ALDH1A1 (0.47) ALDH1A1TDP1MEN1KMT2AMAOA
SCHEMBL1999472 0.86 ALDH1A1 (0.69) ALDH1A1TDP1MEN1KMT2AMAOA
SCHEMBL26167530 0.84 ALDH1A1 (0.45) ALDH1A1TDP1MEN1KMT2AS100A4
SCHEMBL29565907 0.84 ALDH1A1 (0.45) ALDH1A1TDP1MEN1KMT2AS100A4
SCHEMBL1251652 0.82 TDP1 (0.69) ALDH1A1TDP1MEN1KMT2AMAOA
SCHEMBL29566197 0.82 HPGD (0.42) ALDH1A1TDP1MEN1KMT2AS100A4
SCHEMBL26164182 0.82 HPGD (0.42) ALDH1A1TDP1MEN1KMT2AS100A4
SCHEMBL29565972 0.81 PDE7A (0.46) ALDH1A1TDP1KMT2AS100A4PTPRC
SCHEMBL26164138 0.81 PDE7A (0.46) ALDH1A1TDP1KMT2AS100A4PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 US disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALDH1A1 263/4885TDP1 1863/4885MEN1 3437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.